We are a research group in the BioMedical Engineering Department and International Cancer Institute at Peking University. Our lab is primarily a computational biology/bioinformatic group with both ‘wet’ and ‘dry’ labs that develop and use a wide range of genomic and epigenomic sequencing technologies along with bioinformatic methods to explore biomedical questions. Our aim is to explore and understand transcriptomic and epigenetic regulation in both normal and abnormal cells in varied life process. Despite of almost the same copies of genome, cells from different tissues, developmental stages or healthy status display varied functions and phenotypes mainly due to differential gene transcription, in which chromatin and epigenetic regulation plays key roles. Therefore, We are focusing on (but not restricted to) studying how cell fates are controlled by chromatin and epigenome in human health and disorders to provide novel therapy directions to fight against diseases.
Our lab currently focus on the following directions:
We are looking for passionate new PhD students, Postdocs, and Research Assistants to join the team (more info) !
We are grateful for funding from NSFC.
22. March 2023
The Lai Lab website at github is now open. Welcome!
4. September 2023
Welcome new lab members, Dongchen He and Tong Liu!